Bergamot also makes an impor- tant contribution with regard to the “healthiness” of the en- dothelium: the cell tissue that lines the inner surface of blood vessels and lymphatic vessels, as well as the heart chambers. The flavonoids in Bergamot juice help to increase the activity of certain enzymes with an antioxidising effect, and so limit the production of oxygen free radicals in the vascular wall and improve the production of nitric oxide in endothelial cells. Therefore, drinking a glass of Bergamot juice even helps to keep the heart healthy.